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What happens to the nomination submission when you rate the nomination 4 stars or higher in how much you want to accept it, but the accessibility 3 stars or lower?
I would be more specific and clear with the discussion title, but the title would be too long and would not fit the character limit.
No one can tell you that definitively. Your single vote is not as powerful as you think. Just rate it the way you think it deserves and move on.
3* for location just means "I don't know." It definitely does not tank a nomination.
(Back in Google+ days), Niantic said that hopefully, it'll hit a reviewer who has been there and knows. Otherwise, if location gets all 3*, meaning no one knew where it was, they'll trust the "boots on the ground" nominator.
We don't know the answer to this and Niantic is tight-lipped about the details of how reviewer responses are used.